Bioreactors for Stem Cell Expansion and Differentiation (Gene and Cell Therapy)

Bioreactors for Stem Cell Expansion and Differentiation (Gene and Cell Therapy)

by JoaquimM.S.Cabral (Editor), Claudia Lobatoda Silva (Editor)

Synopsis

An international team of investigators presents thought-provoking reviews of bioreactors for stem cell expansion and differentiation and provides cutting-edge information on different bioreactor systems. The authors offer novel insights into bioreactor-based culture systems specific for tissue engineering, including sophisticated and cost-effective manufacturing strategies geared to overcome technological shortcomings that currently preclude advances towards product commercialization. This book in the fields of stem cell expansion, bioreactors, bioprocessing, and bio and tissue engineering, gives the reader a full understanding of the state-of-art and the future of these fields.

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More Information

Format: Illustrated
Pages: 334
Edition: 1
Publisher: CRC Press
Published: 26 Oct 2018

ISBN 10: 1498795900
ISBN 13: 9781498795906

Author Bio
Joaquim M.S. Cabral is a Professor of Biological Engineering, in the Department of Bioengineering at Instituto Superior Tecnico (IST), University of Lisbon, Portugal. He is the founding head of department and director of the Institute for Bioengineering and Biosciences. Joaquim Cabral's research focuses on novel developments in bioprocess engineering and stem cell bioengineering. His research includes stem cell bioprocessing and manufacturing, addressing the ex-vivo expansion, controlled differentiation and purification of hematopoietic stem cells, mesenchymal stem cells, and pluripotent stem cells (both ESC and iPSC). Claudia Lobato da Silva is an Assistant Professor in the Department of Bioengineering, Instituto Superior Tecnico, University of Lisbon, Portugal. Her research interests involve the development of novel methods to isolate and purify stem cells, and establish optimal conditions for the maximization of expansion of umbilical cord blood-derived hematopoietic stem/progenitor cells, as well as developing bioreactor strategies for the clinical-scale production of mesenchymal stem/stromal cells from different human sources.