Introduction to Proteins: Structure, Function, and Motion, Second Edition (Chapman & Hall/CRC Computational Biology Series)

Introduction to Proteins: Structure, Function, and Motion, Second Edition (Chapman & Hall/CRC Computational Biology Series)

by Amit Kessel (Author), Amit Kessel (Author), Nir Ben-Tal (Author)

Synopsis

Introduction to Proteins shows how proteins can be analyzed in multiple ways. It refers to the roles of proteins and enzymes in diverse contexts and everyday applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior.

This edition includes a brand-new chapter on enzymatic catalysis and biochemistry, an in-depth discussion of G-protein-coupled receptors (GPCRs), and a wider-scale description of methods for studying proteins.

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More Information

Format: Illustrated
Pages: 932
Edition: 2
Publisher: Chapman and Hall/CRC
Published: 17 May 2018

ISBN 10: 1498747175
ISBN 13: 9781498747172

Author Bio
Dr. Amit Kessel obtained his master's degree in experimental biochemistry at Tel-Aviv University, studying the innate response of human blood cells to pathogenic bacteria. During his Ph.D. studies he trained as a computational biologist, investigating the molecular basis of peptide-membrane interactions and the mechanisms of antibacterial peptides. In his post-doctoral research at Columbia University, Dr. Kessel continued studying proteins at the molecular level, focusing on various physicochemical aspects of protein-protein interactions. In 2010 he co-founded ES-IS Technologies, a company that designed novel enzymatic solutions for the pharmaceutical industry, and he headed the company's R&D department. He is currently involved in several academic and industrial biotech initiatives, focusing on experimentally-guided protein structure prediction and on the in-vitro construction of protein-based nanoparticles. Prof. Nir Ben-Tal obtained his bachelor's degree in biology, chemistry, and physics at the Hebrew University and his D.Sc. in Chemistry at the Technion, Israel Institute of Technology. He carried out his postdoctoral training as a computational biophysicist at Columbia University, and later joined the Department of Biochemistry and Molecular Biology at Tel Aviv University. His research covers various aspects of computational biology with a focus on structural bioinformatics and the protein universe. In particular, his laboratory has predicted the 3- dimensional structures of a number of transmembrane proteins, thereby providing molecular insight into their mechanisms. His lab also develops the ConSurf web-server for the detection of functional regions by mapping evolutionary data onto protein structures (jointly with the Mayrose and Pupko labs).