The Human Immunodeficiency Virus: Biology, Immunology, and Therapy

The Human Immunodeficiency Virus: Biology, Immunology, and Therapy

by EmilioEmini (Editor)

Synopsis

The past few years have witnessed an explosive increase in our collective knowledge of the biology of the human immunodeficiency virus (HIV). Researchers have acquired new understanding of the virus's biochemistry, molecular biology, pathogenesis, genetics, and immunobiology. Resulting therapeutic advances have significantly prolonged the lives of thousands. Yet, the need to develop better therapies is ever more acute and--given the virus's continued spread through the human population--the need for an effective vaccine is urgent. These goals can be accomplished only through the experienced synthesis of information from the many disciplines participating in HIV research and through the insights of new investigators. This volume is designed to lower the barriers imposed on investigators by the sheer volume of available information--information that often can be found only in far-flung and specialized journals. It provides, in a single resource, an in-depth overview of the diverse areas that constitute HIV research. The result is a broad introduction for students and researchers new to the field as well as an integrated overview for researchers specialized in particular areas of HIV investigation. The volume will also benefit those seeking technical understanding of the virus's biology, including physicians treating HIV-infected patients. Each chapter is a comprehensive presentation of one area of current AIDS research--including work on the virus life cycle, epidemiology, genetics, protease and reverse transcriptase inhibitors, receptor and co-receptor interactions, therapeutic targets, clinical treatment, immunobiology, and vaccines--written by a leading researcher in that area. The contributors are Jon P. Anderson, Jan Balzarini, Elana Cherry, Thomas J. Coates, Chris Collins, Jon H. Condra, Mark B. Feinberg, Richard B. Gaynor, Matthias Gotte, Daria J. Hazuda, Spyros Kalams, Nathaniel R. Landau, Gerald H. Learn, Norman L. Letvin, James I. Mullins, Willscott E. Naugler, David Nickle, Matthew Rain, Allen G. Rodrigo, Daniel Shriner, Shalom Spira, Mario Stevenson, Todd Summers, Catherine Ulich, Joseph P. Vacca, Mark A. Wainberg, Bruce D. Walker, and Yang Wang.

$211.38

Quantity

20+ in stock

More Information

Format: Hardcover
Pages: 546
Edition: illustrated edition
Publisher: Princeton University Press
Published: 07 Jan 2002

ISBN 10: 0691004544
ISBN 13: 9780691004549
Book Overview: This book is written by experts in the field and focuses on both HIV therapy and prevention. It is well illustrated, highly informative, and provides authoritative and completely up-to-date accounts of a complex subject in a manner that could not be achieved by one or a few authors. It will be an excellent resource for all people with the desire or need for a sophisticated account of HIV/AIDS research and its future challenges for some years to come. -- Robert C. Gallo, Director and Professor, Institute of Human Virology

Media Reviews
Emini, one of the leading scientists in antiviral research, has edited an excellent treatise... Each chapter is written by an outstanding investigator in the field, and as a result this book provides an accurate and comprehensive review of the literature up to 2000. --Choice Is it realistic to produce an up-to-date textbook on HIV and AIDS? Emilio Emini has made a brave attempt, persuading several of the best investigators in the field to write authoritative chapters... Overall, this book provides a comprehensive account of anti-HIV drugs and potential drugs and targets, based on what was known as of the end of the 1990s. --Robin A. Weiss, PH.D., New England Journal of Medicine A useful review of immunology, and therapy of the Human Immunodeficiency Virus. --John P. Phair, Quarterly Review of Biology A superb and comprehensive volume that summarizes all that is taking place in HIV research at the present time... [T]he leading comprehensive treatise on HIV research. --Pascal James Imperato, Journal of Community Health
Author Bio
Emilio A. Emini is the Vice President of Vaccine and Antiviral Research at the Merck Research Laboratories. These he led the biological basic research team that developed indinavir, one of the first HIV protease inhibitors, as well as the team involved in the initial discovery of efavirenz, another of the highly active therapeutic agents used to treat of HIV infection. Over the past few years, Dr. Emini has worked toward the development of an HIV vaccine. He holds a Ph.D. in virology from Cornell University's Graduate School of Medical Sciences.