Selection Bias and Covariate Imbalances (Statistics in Practice)

Selection Bias and Covariate Imbalances (Statistics in Practice)

by Berger (Author)

Synopsis

Selection bias can, and does, occur, even in randomized clinical trials. Steps need to be taken in order to ensure that this does not compromise the integrity of clinical trials; hence Selection Bias and Covariate Imbalances in Randomized Clinical Trials offers a comprehensive treatment of the subject and the methodology involved. This book:

  • Provides an overview of the hierarchy of study designs, and justifies the position of randomised trials at the top of this hierarchy.
  • Discusses the strengths and defects of randomisation, and provides real evidence to justify concern regarding its defects.
  • Outlays the damaging consequences that selection bias causes when it does occur.
  • Considers courses of action that can be taken to manage/ contain the problem.
  • Presents methods that can be used to detect selection bias in randomised trials, and methods to correct for selection bias.
  • Concludes by providing a comprehensive plan for managing baseline imbalances and selection bias in randomised trials, and proposing open problems for future research.

Illustrated with case studies, this book introduces groundbreaking ideas and research that will be invaluable to researchers and practitioners who design and analyse clinical trials. It will also be of interest to graduate students within the field of biostatistics.

$89.03

Quantity

20+ in stock

More Information

Format: Illustrated
Pages: 220
Edition: 1
Publisher: John Wiley & Sons
Published: 17 May 2005

ISBN 10: 0470863625
ISBN 13: 9780470863626

Media Reviews
recommended to all practitioners and researchers in the field of clinical trials ( Biometrics, December 2005)

informative and interesting to read (Phamaceutical Statistics Volume 5:2)