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Targeting Protein Kinases for Cancer Therapy

Targeting Protein Kinases for Cancer Therapy

by Mary E . Gerritsen (Author), David J . Matthews (Author)

  • New

    Hardcover 2010

    $166.49
Synopsis

This book provides an overview of different protein kinases structure, function, regulation, and their role in cancer. Itcombines kinase biology with chemistry and pharmacologyapplications for discovery and development of cancer drugs. Thetext also describes existing and emerging kinase inhibitors,focusing mostly on small molecules but also alternative approacheslike therapeutic antibodies. Provides an important resource thathelps pharmaceutical researchers understand and work in thisdynamic area of cancer drug research.

$166.49

Quantity

1 in stock

More Information

Format: Hardcover
 Pages: 702
 Edition: 1
 Publisher: Wiley-Blackwell
Published: 12 Mar 2010
ISBN 10: 0470229659
ISBN 13: 9780470229651

Media Reviews
The comprehensive coverage makes the book highly recommendable for beginners and expert researchers in oncology and should be present on their shelves. ( ChemMedChem, November 2010)
Author Bio
DAVID J. MATTHEWS is Executive Director of OncologyDiscovery at Exelixis, where he is responsible for cancer drugdiscovery. For more than fifteen years, Dr. Matthews has beeninvolved in drug discovery projects in industry, with particularfocus on small molecule inhibitors. He has twenty scientificpublications and multiple patents to his credit. MARY E. GERRITSEN is Vice President of Molecular andCellular Pharmacology at Exelixis, where she is in charge ofcell-based screening in preclinical research and of biomarkerstudies for clinical development compounds in Phase I and IIstudies. Her prior industry experience includes positions atGenentech, Bayer and Millennium Pharmaceuticals. She has authoredmore than one hundred peer-reviewed articles and twenty-six bookchapters and is an inventor on forty-two issued patents.