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Cell Polarity in Development and Disease (Perspectives in Translational Cell Biology)

Cell Polarity in Development and Disease (Perspectives in Translational Cell Biology)

by Douglas Houston (Author)

  • New

    Paperback 2017

    $91.33
Synopsis

Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research.

$91.33

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1 in stock

More Information

Format: Paperback
 Pages: 236
 Publisher: Academic Press
Published: 02 Nov 2017
ISBN 10: 0128024380
ISBN 13: 9780128024386
Book Overview: Offers insights into the basic molecular mechanisms of diseases that arise as a result of a loss of ordered organization and intrinsic polarity

Author Bio
Douglas Houston is a Professor at the University of Iowa. His research is focused on a central problem in developmental biology: how a single-celled egg differentiates into an organism containing many different cell and tissue types. Using frog embryos as a model organism, he and his lab have isolated numerous novel genes with potential roles in key pathways of ovum functions, including genes involved in PGC formation, morphogenesis, and TGF-beta and Wnt growth factor signaling.